Charlotte, NORTH%20CAROLINA8 Active Studies

Leukemia Clinical Trials in Charlotte, NORTH%20CAROLINA

Find 8 actively recruiting leukemia clinical trials in Charlotte, NORTH%20CAROLINA. Connect with local research sites and explore new treatment options.

8
Active Trials
8
Sponsors
1,235
Enrolling

Recruiting Leukemia Studies in Charlotte

RecruitingCharlotte, NORTH%20CAROLINANCT06852222

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Acute Myeloid Leukemia (AML)

The purpose of this study is to assess how bleximenib and Venetoclax (VEN)+ Azacitidine (AZA) works as compared to placebo and VEN+AZA alone for the treatment of participants with Acute Myeloid Leukem...

600 participants
Janssen Research & Development, LLC
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RecruitingCharlotte, NORTH%20CAROLINANCT06043817

First-In-Human Study of STX-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations

Study STX-721-101 is an open label, Phase 1/2 study evaluating the safety, tolerability, pharmacokinetic (PK) exposure, and preliminary antitumor activity of STX-721 in participants with non-small cel...

185 participants
Antares Therapeutics, Inc
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RecruitingCharlotte, NORTH%20CAROLINANCT04801797

Venetoclax + Azacitidine vs. Induction Chemotherapy in AML

This research is being done to assess the therapeutic activity of a promising combination (azacitidine and venetoclax) versus conventional cytotoxic chemotherapy in induction-eligible patients with ac...

172 participants
Massachusetts General Hospital
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RecruitingCharlotte, NORTH%20CAROLINANCT04895436

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study is to assess retreatment with venetoclax-obinutuzumab (VenG) in participants previousl...

75 participants
AbbVie
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RecruitingCharlotte, NORTH%20CAROLINANCT05955261

A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia

This is a phase 2 study to test the hypothesis that venetoclax in combination with standard chemotherapy will be tolerable and active in pediatric patients with newly diagnosed acute myeloid leukemia ...

70 participants
St. Jude Children's Research Hospital
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RecruitingCharlotte, NORTH%20CAROLINANCT06651970

Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure

This will be a global Phase IV, open-label, randomised study to evaluate the safety and tolerability of acalabrutinib (monotherapy, 100 mg orally \[po\], twice daily \[bd\]) compared to investigator's...

60 participants
AstraZeneca
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RecruitingCharlotte, NORTH%20CAROLINANCT06680752

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

This is a phase I/2, interventional, open-label, multicenter study to assess the safety and efficacy of ARD103 in patients with relapsed or refractory acute myeloid leukemia or myelodysplastic syndrom...

49 participants
ARCE Therapeutics, Inc.
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RecruitingCharlotte, NORTH%20CAROLINANCT04964518

A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML)

This is a Phase Ib/II, open-label, multi-center study evaluating the safety, tolerability, efficacy and PK of APG-2575 in combination with Azacitidine in the patients with AML/MPAL or MDS/CMML. The st...

24 participants
Ascentage Pharma Group Inc.
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About Leukemia Clinical Trials in Charlotte

Leukemia is a group of blood cancers that develop in the bone marrow and result in abnormal white blood cells. Types include acute myeloid (AML), acute lymphoblastic (ALL), chronic myeloid (CML), and chronic lymphocytic (CLL). Treatment varies by type and may include chemotherapy, targeted therapy, and stem cell transplant.

There are currently 8 leukemia clinical trials recruiting participants in Charlotte, NORTH%20CAROLINA. These studies are seeking a combined 1,235 participants. Research is being sponsored by Janssen Research & Development, LLC, Antares Therapeutics, Inc, Massachusetts General Hospital and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Leukemia Clinical Trials in Charlotte — FAQ

Are there leukemia clinical trials in Charlotte?

Yes, there are 8 leukemia clinical trials currently recruiting in Charlotte, NORTH%20CAROLINA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Charlotte?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Charlotte research site will contact you about next steps.

Are clinical trials in Charlotte free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Charlotte studies also compensate for your time and travel.

What leukemia treatments are being tested?

The 8 active trials in Charlotte are testing new therapies including novel drugs, biologics, and treatment approaches for leukemia.

Data updated March 2, 2026 from ClinicalTrials.gov